Sleeping pills work best and are safest if used for a short time and are even more effective if you change what is going on in your life that is causing you to not be able to sleep. I started taking Tylenol PM several years ago and in the beginning they worked fine. But the longer I used them, the less effective they were. Acetophetamine has the potential side effect of that of causing liver damage.

If you are taking large doses of Tylenol PM and have been taking for a long time you should consider having your liver checked to make sure there hasn’t been any damage done. Although it is not usually common, symptoms of liver damage include abdominal pain, nausea, can cause yellowing of the skin or eyes, and unusual bleeding or severe fatigue. Reported blood problems such as easy or unusual bleeding or bruising can also occur when taking too much Tylenol PM. Another possible side effect of taking Tylenol PM is the potential for having low blood sugar. Symptoms of low blood sugar would include fatigue, increased hunger, fainting or dizziness.